Boyan, A., Westerman, D., & Daniel, E. S. (2016). Rooting with your Rivals: Social Presence in Fantasy Sports. In N. D. Bowman, J. S. W. Spinda & J. Sanderson (Eds.), Fantasy Sports and the Changing Sports Media Industry : Media, Players, and Society (pp. 79-97). Lanham: Lexington Books.
Russell, J.-e., Van Horne, S., Ward, A. S., Bettis, E. A., Sipola, M., Colombo, M., et al. (2016). Large Lecture Transformation: Adopting Evidence-Based Practices to Increase Student Engagement and Performance in an Introductory Science Course. Journal of Geoscience Education, 64(1), 37-51.
Abstract: This study investigated students’ attitudes, engagement, satisfaction, and performance in Introduction to Environmental Science after it was transformed from a typical large lecture to a student-centered learning environment. The instructors of the course collaborated with the Office of Teaching, Learning & Technology and radically redesigned the course by adopting evidence-based pedagogical methods and instructional technology to offer a rich active learning environment. Students’ engagement, satisfaction, and performance in the transformed course were compared to the students in the same course that was traditionally taught in a previous semester in order to measure the effect of the transformed course on student learning. Four self-reported surveys and a focus group interview were administered during the semester, and performance scores, prior learning data, and demographic information were collected at the end of the semester. The assessment results indicate that the students in the transformed course prepared for the class significantly more, engaged in the course significantly better, and were significantly more satisfied with the course than were the students in the traditional lecture-format course. Most of all, multiple linear regression indicates that the students in the transformed course earned, on average, about three-fourths of a letter grade higher on their final grade after controlling for cumulative grade point average. The students in the transformed course reported that online learning materials and frequent formative assessments using online quizzes were helpful in their learning, and they perceived the course was relevant to real-world applications that matter to their daily life.
Schoene, M. (2016). Urban Continent, Urban Activism? European Cities and Social Movement Activism. Global Society, 1-22.
Abstract: The European Union is currently experiencing a major protest wave. Citizens all over the continent are taking to the streets in droves to express their dissatisfaction with austerity policies, high unemployment, ineffective leadership and other issues. Many of these protests have been centred in large cities, but while some scholarly work notes the expressly urban nature of contemporary social movement activity, no studies test the effect of urban residential status on the likelihood of social movement participation in the presence of other factors. I hypothesise that cities positively influence the prevalence of social movement activity in the countries of the European Union. Using the multilevel 5th wave of the European Social Survey, I examine how urbanity, resources and grievances influence the likelihood of participation in four different forms of activism: wearing a protest badge, boycotting a product, signing a petition and participating in a demonstration. A series of multilevel mixed-effects regression models indicate that resources and urban status best predict the likelihood of participation in the four activities, indicating that cities offer better environments for social movement activity. I conclude with a discussion about European movement activity and urban society.
Parr, C., & Linich, C. (2016). Supra! A Feast of Georgian Song. Milwaukee, WI: Hal Leonard.
Publishers Description: Traditional choirs, folk ensembles or any other group of singers will enjoy this collection of songs from the Republic of Georgia selected, notated and recorded by Clayton Parr and Carl Linich. Like folk songs from the rest of the world, Georgian songs are traditionally connected with events of daily life – work songs, laments, lullabies, songs about historical events or figures, ritual songs, healing songs, traveling songs, comic songs, and dance songs. Table songs are a particularly important genre, and the tradition of the supra (ritual banquet), with elaborate toasts and songs, occupies a central position in Georgian traditional culture. Traditionally, these songs are in three polyphonic voice parts, and the authors have provided many pedagogical tools for learning: recordings, pronunciation guides, lyric sheets, song backgrounds and recordings.
Guseman, E. H., Eisenmann, J. C., Betz, H. H., Pfeiffer, K. A., & Paek, H.-J. (2016). Screen time, sleep and overweight among low-income 8-12 year old youth. Journal of Behavioral Health, 5(2), 39-44.
Abstract: This paper describes a cross-sectional study of the combined influence of sleep and screen time behaviors on the odds of overweight and obesity among low-income youth. One of those most notable strengths of this study is the significant proportion of our sample who identify as members of an ethnic minority, most notably Hispanic and African American (approximately 84% of the total sample). This improves upon previous studies that often report data on almost entirely white samples, who often also do not qualify as low-income. Thus, we feel that this study makes a substantial contribution to the literature in spite of the null findings.
Baker, V. L., Greer, J., Lunsford, L. G., Pifer, M. J., & Ihas, D. (2016). Documenting the Aspiration Gap in Institutional Language About Undergraduate Research, Scholarship, and Creative Work. Innovative Higher Education, 1-17.
Abstract: We conducted a content-analysis of the websites of 100 institutional members of the Council of Undergraduate Research in order to examine the relationship between messages communicated on websites as compared to messages expressed within institutional procedures and policies. Findings show that public research institutions were more likely than baccalaureate institutions to have an Office of Undergraduate Research. Further incentives and supports provided by such offices are predominantly directed to students. Lastly, our analysis of promotion and tenure policies reveals that only 14 institutions out of the 100 in our sample explicitly mentioned mentoring undergraduate researchers in the evaluation criteria for faculty members. We offer implications for research and practice.
Rose, W. (2016). C. Wright Mills on Law and Society: Hidden in Plain Sight? In G. Oakes (Ed.), The Anthem Companion to C. Wright Mills. London: Anthem Press.
Guenin-Lelle, D. (2016). The story of French New Orleans : history of a Creole city. Jackson: University Press of Mississippi.
“What is it about the city of New Orleans? History, location, and culture, continue to link it to France while distancing it culturally and symbolically from the United States. This book explores the traces of French language, history, and artistic expression that have been present there over the last three hundred years. This volume focuses on the French, Spanish, and American colonial periods to understand the imprint that French socio-cultural dynamic left on the Crescent City. The migration of Acadians to New Orleans at the time the city became a Spanish dominion and the arrival of Haitian refugees when the city became an American territory oddly reinforced its Francophone identity. However, in the process of establishing itself as an urban space in the antebellum South, the culture of New Orleans became a liability for New Orleans elite after the Louisiana Purchase. New Orleans and the Caribbean share numerous historical, cultural, and linguistic connections. The book analyzes these connections and the shared process of creolization occurring in New Orleans and throughout the Caribbean Basin. It suggests ‘French’ New Orleans might be understood as a trope for unscripted ‘original’ Creole social and cultural elements. Since being Creole came to connote African descent, the study suggests that an association with France in the minds of whites allowed for a less racially-bound and contested social order within the United States.” (Provided by publisher)
Menold, C. A., Grove, M., Sievers, N. E., Manning, C. E., Yin, A., Young, E. D., et al. (2016). Argon, oxygen, and boron isotopic evidence documenting 40ArE accumulation in phengite during water-rich high-pressure subduction metasomatism of continental crust. Earth and Planetary Science Letters, 446, 56-67.
Abstract: The Luliang Shan area of the North Qaidam high pressure (HP) to ultrahigh pressure (UHP) metamorphic terrane in northwestern China features thick, garnet- and phengite-rich metasomatic selvages that formed around gneiss-hosted mafic eclogite blocks during HP conditions. Here we present new 40Ar/39Ar, δ18O, and δ11B results from a previously studied 30 m, 18 sample traverse that extends from the host gneiss into a representative eclogite block. Previous thermobarometry and new mica-quartz oxygen isotope thermometry from the traverse reveal that the phengite-rich selvage formed at temperatures similar to those recorded by the eclogites at peak pressure. Quartz and white mica δ18O data from the selvage cannot be explained by simple mixing of gneiss and eclogite, and indicate a fluid/rock ratio >1 during regional-scale infiltration of high δ18O (ca. 14‰) fluids. Heavy δ18O overgrowths of metamorphic zircon over lighter δ18O detrital grains indicate that the gneiss was similarly affected. Starkly contrasting boron content and δ11B compositions for the host gneiss and the selvage also cannot be explained by local-scale devolatilization of the gneiss to form the selvage. Instead, the boron systematics are best attributed to two distinct phases of fluid infiltration: (1) low-boron selvage phengite with δ11B from −10 to −30‰ grew under HP conditions; and (2) tourmaline and boron-rich muscovite with generally positive δ11B crystallized in the host gneiss under subsequent lower pressure epidote–amphibolite facies conditions as the Luliang Shan gneiss terrane was exhumed past shallower portions of the subduction channel. Consistent with observations made worldwide, we were able to identify uptake of excess argon (40ArE) in phengite as a high pressure phenomenon. Phengite 40Ar/39Ar ages from massive eclogite exceed the ca. 490 Ma zircon U–Pb age of eclogite metamorphism by a factor of 1.5. However, phengite ages from the more permeable schistose selvage were even older, exceeding the time of eclogite formation by a factor of 1.7. In contrast, lower pressure retrograde muscovite present within the host gneiss and in discrete shear zones cutting the selvage yield 40Ar/39Ar ages that were younger than the time of HP metamorphism and consistent with regional cooling age patterns. Our observation of high 40ArE concentrations in phengite from schistose rocks infiltrated by regionally extensive fluids at HP conditions runs contrary to widely held expectations. Conventional wisdom dictates that low phengite/fluid partition coefficients for argon () coupled with the dry, closed systems conditions that are widely reported to characterize HP metamorphism of continental crust explains why high concentrations of 40ArE partitions are able to accumulate within phengite. We alternatively propose that phengite/fluid partition coefficients for argon increase linearly with pressure to values as high as 10−2 to allow phengites to accumulate large amounts of 40ArE from aqueous fluids under HP to UHP conditions
Zonneveld, J. P., Bartels, W. S., Gunnell, G. F., & McHugh, L. P. (2015). Borings in early Eocene turtle shell from the Wasatch Formation, South Pass, Wyoming. Journal of Paleontology, 89(5), 802-820.
Abstract: Borings in fossil turtle shells collected from the lowermost beds of the early Eocene Cathedral Bluffs Tongue of the Wasatch Formation in the northwestern part of the Green River Basin near South Pass, Wyoming, are herein described. Individual turtle shells in the study area are characterized by as few as one or two and as many as >100 borings. The borings include both non-penetrative forms (those which do not pass fully though the shell) as well as penetrative forms (those which pass fully from the exterior to the interior surface of the shell). All non-penetrative forms occur on external surfaces of the carapace and plastron (i.e. those that would have been accessible while the host taxon was alive). Two new ichnogenera and four new ichnospecies are established to describe these borings. Karethraichnus (new ichnogenus) includes three ichnospecies: K. lakkos (new ichnospecies), K. kulindros (new ichnospecies), and K. fiale (new ichnospecies). Karethraichnus lakkos are shallow (non-penetrating), hemispherical pits with rounded, to flattened bases. Karethraichnus kulindros are deep, non-penetrative traces with a cylindrical profile, an axis approximately perpendicular to the substrate surface and with rounded to flattened, hemispherical termini. Karethraichnus fiale are penetrative traces with a cylindrical to bi-convex or flask-shaped profile, and an axis approximately perpendicular to the substrate surface. Thatchtelithichnus (new ichnogenus) Thatchtelithichnus holmani (new ichnospecies) consist of non-penetrative borings into a bone substrate. They consist of a ring-shaped trace, with a central pedestal or platform. The position of the borings on the shells, and evidence of syn-emplacement healing of the borings in several of the turtles, indicates that these borings were emplacement by ectoparasites/mesoparasites while the animals were living. Similar traces in modern emydid turtles are attributed to ticks, leeches, or spirorchid liver flukes.
Judd, W. S., Majure, L. C., Skean, J. D., & Neubig, K. M. (2015). Miconia Abscondita (Melastomataceae: Miconieae), a New Species from the Massif De La Hotte, Haiti: Rediscovered in Herbaria after being Hidden for Nearly Nine Decades. Rhodora, 117(971), 317-341.
Abstract: In the course of a taxonomic revision of several clades of Greater Antillean Melastomataceae, we discovered a previously undescribed species, Miconia abscondita, from the Massif de la Hotte, Haiti. Miconia abscondita is based on a vegetative collection by Swedish botanist, E. L. Ekman, which was made in 1926. This new species is a member of the Mecranium clade, a group well supported on the basis of both morphological and molecular data, but which is highly embedded within the phylogenetic structure of the genus Miconia. Miconia abscondita is clearly placed within the Mecranium clade on the basis of DNA sequence data, and this placement also is supported by the form of its hairs and, especially, the pattern of stem indumentum; however, it matches no currently described species. Miconia abscondita is thus described, illustrated, and compared with putatively related and/or phenetically similar species. The discovery of M. abscondita brings to 25 the number of recognized species within the Mecranium clade and to 11 the number of species occurring in the Massif de la Hotte, Haiti, a region of exceptional biodiversity that is under continuous threat from anthropogenic pressure.
Uesugi, A., Rajesh, S. V., Abhayan, G. S., Chase, B., Rawat, Y. S., Patel, A., et al. (2015). Indus Ceramics from Desalpur, Kachchh, Gujarat. Heritage: Journal of Multidisciplinary Studies in Archaeology, 3, 180-218.
Abstract: The Harappan site of Desalpur is located in the western part of Kachchh District, Gujarat, India. This site was dicovered in the 1950s and was excavated in 1963‐64 (IAR 1963‐64), the brief report of which gives us the great potentiality of this site as this site was reported to have massive peripheral walls along with cultural deposits more than 2 m in thickness. The discovery of steatite and copper seals also adds importance to this site. However, the details of the excavations have not been published making it difficult to properly evaluate the significance of this site.
The Kachchh region has been known for the distribution of many Indus sites such as Dholavira, Juni Kuran, Kanmer, Shikarpur, Surkotada, Khirsara and so on. This region, surrounded by the Rann, which is presumed to have been filled with seawater during the third millennium BC, is highly likely to have flourished with sea trade as well as with land route trade connecting with Sindh, Balochistan and Gujarat. Therefore the investigations of archaeological sites of this region (Fig. 1) can contribute for better understanding of the urban society of the Indus Civilization that was sustained by rigorous inter‐regional interactions and trading networks. In this sense, the site of Desalpur has an imporatnce not only for establishing the local chronology but also for understanding the inter‐regional interactions between the Arabian Penninsula, Sindh and Gujarat.
This paper examines the ceramic evidence collected from Desalpur by Department of Archaeology, the University of Kerala in order to assess the archaeological importance of this site.
Tsou, P.-S., Rabquer, B. J., Ohara, R. A., Stinson, W. A., Campbell, P. L., Amin, M. A., et al. (2016). Scleroderma dermal microvascular endothelial cells exhibit defective response to pro-angiogenic chemokines. Rheumatology, 55(4), 745-754.
Objectives. Angiogenesis plays a critical role in SSc (scleroderma). The aim of this study was to examine the expression of growth-regulated protein-γ (Gro-γ/CXCL3), granulocyte chemotactic protein 2 (GCP-2/CXCL6) and their receptor CXCR2 in endothelial cells (ECs) isolated from SSc skin and determine whether these cells mount an angiogenic response towards pro-angiogenic chemokines. The downstream signalling pathways as well as the pro-angiogenic transcription factor inhibitor of DNA-binding protein 1 (Id-1) were also examined.
Methods. Skin biopsies were obtained from patients with dcSSc. ECs were isolated via magnetic positive selection. Angiogenesis was measured by EC chemotaxis assay.
Results. Gro-γ/CXCL3 and GCP-2/CXCL6 were minimally expressed in both skin types but elevated in SSc serum. Pro-angiogenic chemokine mRNA was greater in SSc ECs than in normal ECs. SSc ECs did not migrate to vascular endothelial growth factor (VEGF), Gro-γ/CXCL3, GCP-2/CXCL6 or CXCL16. The signalling pathways stimulated by these chemokines were also dysregulated. Id-1 mRNA in SSc ECs was lower compared with normal ECs, and overexpression of Id-1 in SSc ECs increased their ability to migrate towards VEGF and CXCL16.
Conclusion. Our results show that SSc ECs are unable to respond to pro-angiogenic chemokines despite their increased expression in serum and ECs. This might be due to the differences in the signalling pathways activated by these chemokines in normal vs SSc ECs. In addition, the lower expression of Id-1 also decreases the angiogenic response. The inability of pro-angiogenic chemokines to promote EC migration provides an additional mechanism for the impaired angiogenesis that characterizes SSc.
Pifer, M. J., & Baker, V. L. (2016). Stage-Based Challenges and Strategies for Support in Doctoral Education: A Practical Guide for Students, Faculty Members, and Program Administrators. International Journal of Doctoral Studies, 11, 15-34.
Abstract: Studies of doctoral education have included an interest not only in processes, structures, and outcomes, but also in students’ experiences. There are often useful recommendations for practice within individual examinations of the doctoral experience, yet there remains a need to strengthen the application of lessons from research to the behaviors of students and others engaged in the doctoral process. This paper is the first to synthesize research about doctoral education with the particular aim of informing practical strategies for multiple stakeholders. In this article, we summarize findings from a literature review of the scholarship about doctoral education from the past 15 years in a stage-based overview of the challenges of doctoral education. Our aim is to apply theory to practice through the systematic consideration of how research about doctoral education can best inform students and those who support them in the doctoral journey. We first present an overview of the major stages of doctoral education and related challenges identified in the research. We then consider key findings of that research to offer recommendations for doctoral students, faculty members, and administrators within and across stages.
Wilson, D. P. (2016). Protruding Features of Viral Capsids Are Clustered on Icosahedral Great Circles. PLoS ONE, 11(4), e0152319.
Abstract: Spherical viruses are remarkably well characterized by the Triangulation (T) number developed by Casper and Klug. The T-number specifies how many viral capsid proteins are required to cover the virus, as well as how they are further subdivided into pentamer and hexamer subunits. The T-number however does not constrain the orientations of these proteins within the subunits or dictate where the proteins should place their protruding features. These protrusions often take the form of loops, spires and helices, and are significant because they aid in stability of the capsid as well as recognition by the host organism. Until now there has be no overall understanding of the placement of protrusions for spherical viruses, other than they have icosahedral symmetry. We constructed a set of gauge points based upon the work affine extensions of Keef and Twarock, which have fixed relative angular locations with which to measure the locations of these features. This work adds a new element to our understanding of the geometric arrangement of spherical viral capsid proteins; chiefly that the locations of protruding features are not found stochastically distributed in an icosahedral manner across the viral surface, but instead these features are found only in specific locations along the 15 icosahedral great circles. We have found that this result holds true as the T number and viral capsids size increases, suggesting an underlying geometric constraint on their locations. This is in spite of the fact that the constraints on the pentamers and hexamer orientations change as a function of T-number, as you need to accommodate more hexamers in the same solid angle between pentamers. The existence of this angular constraint of viral capsids suggests that there is a fitness or energetic benefit to the virus placing its protrusions in this manner. This discovery may have profound impacts on identifying and eliminating viral pathogens, understanding evolutionary constraints as well as bioengineering for capsid drug delivery systems. This result also suggests that in addition to biochemical attachment restrictions, there are additional geometric constraints that should be adhered to when modifying protein capsids.
DeBruhl, H., Albertson, R., Swider, Z., & Sullivan, W. (2016). Rop, the Sec1/Munc18 homolog in Drosophila, is required for furrow ingression and stable cell shape during cytokinesis. Journal of Cell Science, 129(2), 430-443.
Abstract: Physically separating daughter cells during cytokinesis requires contraction of an actin-myosin ring and vesicle-mediated membrane addition at the cleavage furrow. To identify vesicle trafficking proteins that function in cytokinesis, we screened deficiencies and mutations of candidate genes by live imaging the mitotic domains of the Drosophila embryo. In embryos homozygous for some of these deficiencies, we observed several cytokinesis phenotypes, including slow furrow ingression and increased membrane blebbing. We also found that cytokinesis required the Sec1/Munc18 homolog Rop, which interacts with syntaxin and mediates exocytosis at the plasma membrane. In a temperature-sensitive Rop mutant (Rop(TS)), the contractile ring disassembled during furrow ingression, indicating that maintenance of the ring required vesicle addition. Furthermore, in some dividing Rop(TS) cells, the shape of the daughter cells became unstable, causing cytokinesis failure. These results further highlight the importance of vesicle trafficking in animal cytokinesis and show that vesicle fusion influences cell shape during cytokinesis.
Yoshii, M. (2014). The U.S. Stance Toward the 1962 Sino-Japanese Trade Agreement. Crossroads: Studies on the History of Exchange Relations in the East Asian World, 10, 197-212.
Abstract: On November 9, 1962, Japan concluded a five-year trade agreement with China, promising an exchange of $50 million worth of goods during 1963. U.S. Secretary of State, Dean Rusk, sent a message to Tōkyō criticizing Japan’s approach to Beijing especially as the timing of this deal coincided with the Sino-Indian border war. This paper examines the Kennedy administration’s policy toward Japan’s approach to Beijing. Rusk’s preoccupation with the Cold War and lack of a grasp of East Asian conditions led him to believe that the agreement was Japan’s first step toward recognizing Beijing. In contrast, the department’s East Asian specialists, particularly Ambassador Edwin O. Reischauer, had a better comprehension of the Sino-Japanese relations in the early 1960s based on their historical, cultural, and economic considerations. This paper provides not only the complex layers of the U.S. policy makers’ intentions, but also a fresh new look at the historical relations between Beijing and Tōkyō a decade before China’s mending of relations with the U.S. and Japan.
McCauley, A. M. (Artist). (2016). passage 24. Americas 2016: Paperworks Exhibition, Minot State University, January 12-February 19, 2016.
Walker, R. J., & Christopher, A. N. (2016). Time-of-day preference mediates the relationship between personality and breakfast attitudes. Personality and Individual Differences, 91, 138-143.
Abstract: Personality and time-of-day preference (i.e., chronotype) are two reliable predictors of breakfast behaviors. The current study examined if time-of-day preference mediates the relation between the Big Five personality traits and breakfast-related attitudes and behaviors. Results revealed that conscientiousness, extraversion, and agreeableness predicted healthy breakfast attitudes and behaviors, whereas neuroticism predicted unhealthy breakfast attitudes and behaviors. Importantly, time-of-day preference mediated most of these relationships (except for the agreeableness models). Even when the direct effect of personality on breakfast attitudes and behaviors was not significant, all of the indirect effects through time-of-day preference were significant. Together, these findings indicate that personality differences in breakfast attitudes and behaviors are accounted for by time-of-day preference. These findings also suggest that future work should examine more integrative models of eating behavior to better understand how various individual differences relate to specific attitudes and behaviors.
Albion College alumnus co-author: Ryan Walker, ’12
Kanter, D. E. (2015). Truly In-between People: Situating Latinos in Twentieth-Century Urban History. Journal of Urban History, 41(6), 1143-1151.
Baker, V. L., Lunsford, L. G., & Pifer, M. J. (2015). Systems Alignment for Comprehensive Faculty Development in Liberal Arts Colleges. To Improve the Academy, 34(1-2), 91-116.
Abstract: Using an alignment framework, the authors explore faculty development initiatives in liberal arts colleges in order to understand the connection between organizational priorities and processes as connected to faculty members’ stated needs. The study draws on mixed-methods data from The Initiative for Faculty Development in Liberal Arts Colleges (IFDLAC), including survey and interview data from the 13 member institutions of the Great Lakes Colleges Association (GLCA).The authors offer future implications for faculty development practice.
DeCaro, M. S., Van Stockum, C. A., Jr., & Wieth, M. B. (2016). When Higher Working Memory Capacity Hinders Insight. Journal of Experimental Psychology: Learning, Memory, and Cognition, 42(1), 39-49.
Abstract: Higher working memory capacity (WMC) improves performance on a range of cognitive and academic tasks. However, a greater ability to control attention sometimes leads individuals with higher WMC to persist in using complex, attention-demanding approaches that are suboptimal for a given task. We examined whether higher WMC would hinder insight problem solving, which is thought to rely on associative processes that operate largely outside of close attentional control. In addition, we examined whether characteristics of the insight problems influence whether this negative relationship will be revealed. In Experiment 1, participants completed matchstick arithmetic problems, which require a similar initial problem representation for all problems. Higher WMC was associated with less accurate insight problem solving. In Experiment 2, participants completed insight word problems, which require substantially different representations for each problem. Higher WMC was again negatively associated with insight, but only after statistically controlling for shared variance between insight and incremental problem-solving accuracy. These findings suggest that WMC may benefit performance on fundamental processes common to both incremental and insight problem solving (e.g., initial problem representation), but hinder performance on the processes that are unique to insight (e.g., solution and restructuring). By considering the WMC of the individual, and the nature of the insight task, we may better understand the process of insight and how to best support it.
Engdahl, A. J., Torres, E. A., Lock, S. E., Engdahl, T. B., Mertz, P. S., & Streu, C. N. (2015). Synthesis, Characterization, and Bioactivity of the Photoisomerizable Tubulin Polymerization Inhibitor azo-Combretastatin A4. Organic Letters, 17(18), 4546-4549.
Abstract: Combretastatin A4 is a stilbenoid tubulin binding mitotic inhibitor whose conformation greatly influences its potency, making it an excellent candidate for adaptation as a photoactivatable tool. Herein we report a novel synthesis, the facile isomerization with commercial grade equipment, and biological activity of azo-combretastatin A4 in vitro and in human cancer cells. Photoisomerized azo-combretestatin A4 is at least 200-fold more potent in cellular culture, making it a promising phototherapeutic and biomedical research tool.
Biermeier-Hanson, B. (2015). What About the Rest of Us? The Importance of Organizational Culture in Nepotistic Environments. Industrial and Organizational Psychology, 8(01), 27-31.
Abstract: To date, empirical investigations into whether nepotism, specifically, or social connection preference (SCP), generally, is positive or negative within the realm of organizational scholarship has been limited. Indeed, most of the early discussions in this field on the subject have focused on previous work done outside the organizational area (i.e., Bellow, 2003). A recent Society for Industrial and Organizational Psychology Organizational Frontier Series book on the subject has brought some initial attention to the subject by approaching it from multiple domains within the organizational literature (Jones, 2012). Jones and Stout (2015) have highlighted the possible advantages and disadvantages of SCPs and have taken the stand that SCPs might in fact provide more benefits than drawbacks, particularly given that formalized policies may lead to unfair discrimination.
De Winter, S., Kamischke, E., & Wang, Z. (2015). Automorphisms of strongly regular graphs with applications to partial difference sets. Designs, Codes and Cryptography, 1-15.
Abstract: In this article we generalize a theorem of Benson (J Algebra 15:443–454, 1970) for generalized quadrangles to strongly regular graphs, deriving numerical restrictions on the number of fixed vertices and the number of vertices mapped to adjacent vertices under an automorphism. We then use this result to develop a few new techniques to study regular partial difference sets (PDS) in Abelian groups. Ma (Des Codes Cryptogr 4:221–261, 1994) provided a list of parameter sets of regular PDS with k≤100 in Abelian groups for which existence was known or had not been excluded. In particular there were 32 parameter sets for which existence was not known. Ma (J Stat Plan Inference 62:47–56, 1997) excluded 13 of these parameter sets. As an application of our results we here exclude the existence of a regular partial difference set for all but two of the undecided parameter sets from Ma’s list.